SCHEMBL1376993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1376995	0.93	CYP2C9 (0.54)	CYP2C9LMNAKMT2AMEN1TSHR
	SCHEMBL1523498	0.89	MAOB (0.36)	CYP2C9LMNAKMT2AMEN1RXFP1
	SCHEMBL1522448	0.88	CYP2C9 (0.50)	CYP2C9LMNAKMT2AMEN1POLB
	SCHEMBL1522201	0.87	CYP2C9 (0.51)	CYP2C9KMT2AMEN1POLBROCK2
	SCHEMBL1523868	0.86	KMT2A (0.33)	CYP2C9LMNAKMT2AMEN1TSHR
	SCHEMBL1522396	0.85	CYP2C9 (0.51)	CYP2C9KMT2AMEN1TSHRPOLB
	SCHEMBL1522247	0.83	NR1I2 (0.36)	CYP2C9LMNAKMT2AMEN1TSHR
	SCHEMBL1379855	0.83	NR1I2 (0.36)	CYP2C9LMNAKMT2AMEN1TSHR
	SCHEMBL1522259	0.82	NR1I2 (0.37)	CYP2C9LMNAKMT2AMEN1TSHR
	SCHEMBL1523499	0.82	CYP2C9 (0.42)	CYP2C9LMNAKMT2AMEN1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.