Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB2 | P47870 | 4/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929272 | 0.94 | GABRA1 (0.60) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL8288535 | 0.82 | GABRB2 (0.61) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL2935076 | 0.80 | GABRA1 (0.61) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL2934780 | 0.79 | GABRB2 (0.67) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL8288574 | 0.76 | GABRB2 (0.57) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL13770984 | 0.75 | GABRB2 (0.53) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL8286549 | 0.75 | GABRA1 (0.64) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL2935333 | 0.75 | GABRA1 (0.53) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL2929266 | 0.75 | GABRA1 (0.74) | GABRB2GABRA1GABRA2KDM4EHPGD | |
| SCHEMBL1761287 | 0.75 | GABRA1 (0.74) | GABRB2GABRA1GABRA2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566725-B2 | Imidazo[1,2-A] pyridine anxiolytics | SEPRACOR INC. (US) | 2009-07-28 | — | — | US | disclosed |