Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.74 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.74 |
| ▸ | ALB | P02768 | 2/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.74 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.74 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.74 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308850 | 0.93 | GABRA1 (0.66) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL14889249 | 0.92 | GABRB2 (0.65) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL28395142 | 0.89 | GABRA1 (0.61) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2929266 | 0.89 | GABRA1 (0.74) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL12436585 | 0.88 | GABRA1 (0.60) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL14797241 | 0.88 | GABRA1 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL6011803 | 0.88 | GABRA1 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2929147 | 0.88 | GABRB2 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL2935064 | 0.86 | GABRB2 (0.71) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2309142 | 0.86 | GABRB2 (0.78) | GABRA1GABRB2ALBOPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-217236248-U | Vacuum dryer is used in processing of safe type zolpidem acid | 诚弘制药(威海)有限责任公司 | 2022-08-19 | — | — | CN | claimed |
| US-8183377-B2 | Process for the preparation of imidazopyridines | ELDER PHARMACEUTICALS LTD. | 2012-05-22 | — | — | US | claimed |
| CN-101395156-B | Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof | FERRER INTERNACIONAL, S.A. (ES) | 2011-12-14 | — | — | CN | claimed |
| EP-1917263-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD (IN) | 2010-11-24 | — | — | EP | claimed |
| WO-2010122576-A1 | IMPROVED PROCESS FOR THE PREPARATION OF 6-METHYL-2-[4-METHYL PHENYL] IMIDAZO [1, 2-A] PYRIDINE-3-N, N-DIMETHYL ACETAMIDE. | MATRIX LABORATORIES LTD (IN) | 2010-10-28 | — | — | WO | claimed |
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD. (IN) | 2010-02-11 | — | — | US | claimed |
| US-20090176777-A1 | Imidazo (1,2-a)Pyridin-3-YL-Acetic Acid Hydrazides, Proesses for Their Preparation and Pharmaceutical Uses Thereof | FERRER INTERNACIONAL, S.A. (ES) | 2009-07-09 | — | — | US | claimed |
| EP-1973907-B1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INT (ES) | 2009-05-06 | — | — | EP | claimed |
| CN-101395156-A | Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof | FERRER INT (ES) | 2009-03-25 | — | — | CN | claimed |
| EP-1917263-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | Elder Pharmaceuticals Ltd (IN) | 2008-05-07 | — | — | EP | claimed |
| EP-1803722-A1 | Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-04 | — | — | EP | claimed |
| WO-2007023504-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD (IN) | 2007-03-01 | — | — | WO | claimed |
| US-20070027180-A1 | PROCESS FOR PREPARING ZOLPIDEM | DR. REDDY'S LABORATORIES, INC. | 2007-02-01 | — | — | US | claimed |
| CN-114057729-B | Preparation method of zolpidem | 鲁南制药集团股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114249723-B | Preparation method of zolpidem and key intermediate thereof | 鲁南制药集团股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-115838338-B | Method for preparing amide | 浙江工业大学 | 2024-12-24 | — | — | CN | disclosed |
| US-20020019528-A1 | Process for the preparation of 2-phenyl-imidazo [1, 2-a] pyridine-3-acetamides | DINAMITE DIPHARMA S.P.A. | 2002-02-14 | — | — | US | disclosed |
| EP-1172364-A1 | A process for the preparation of 2-phenyl-imidazo[1,2-A]pyridine-3-acetamides | Dinamite Dipharma S.p.A. (in abbreviated form Dipharma S.p.A.) (IT) | 2002-01-16 | — | — | EP | disclosed |
| US-6281360-B1 | REACTING IMIDAZOPYRIDINE COMPOUND WITH GLYOXYLIC ACID | SYNTHON BV (NL) | 2001-08-28 | — | — | US | disclosed |
| EP-1038875-A2 | Imidazopyridine derivatives and process for making them | Synthon B.V. (NL) | 2000-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019528-A1 | Process for the preparation of 2-phenyl-imidazo [1, 2-a] pyridine-3-acetamides | OTC, ODC1, OXGR1 | GABRA1 2363/4885GABRB2 3240/4885ALB 240/4885 |
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | OTC, ODC1, OGDH | GABRA1 198/4885GABRB2 578/4885ALB 832/4885 |
| US-20090176777-A1 | Imidazo (1,2-a)Pyridin-3-YL-Acetic Acid Hydrazides, Proesses for Their Preparation and Pharmaceutical Uses Thereof | GABRA3, GABRA1, GABRA2 | GABRA1 2/4885GABRB2 11/4885ALB 776/4885 |
| US-20070027180-A1 | PROCESS FOR PREPARING ZOLPIDEM | GABARAP, GABARAPL1, BPGM | GABRA1 35/4885GABRB2 108/4885ALB 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.