Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820986 | 0.85 | GAA (0.53) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6702417 | 0.83 | GAA (0.61) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL5105903 | 0.83 | GAA (0.64) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL13341907 | 0.82 | GAA (0.48) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL7507754 | 0.75 | GAA (0.54) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6604649 | 0.74 | TRPM8 (0.56) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL4893734 | 0.74 | GAA (0.53) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL4905523 | 0.72 | MAPT (0.56) | GAANPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12154292 | 0.72 | RAB9A (0.59) | GAANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL969119 | 0.72 | MEN1 (0.59) | GAANPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740583-B1 | OXADIAZOLONE DERIVATIVES AS PPAR DELTA AGONISTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-01 | — | — | EP | disclosed |