Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19274902 | 0.88 | ALDH1A1 (0.51) | ABCB1USP2ATMALDH1A1KDM4E | |
| SCHEMBL13771828 | 0.83 | ALDH1A1 (0.44) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL3506602 | 0.83 | ABCB1 (0.62) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14388301 | 0.83 | ABCB1 (0.49) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14527723 | 0.77 | CYP1A2 (0.48) | USP2ATMALDH1A1KDM4ENPC1 | |
| SCHEMBL19101787 | 0.76 | APP (0.45) | ABCB1USP2CFTRATMGOPC | |
| SCHEMBL19269681 | 0.73 | USP2 (0.49) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL16425654 | 0.70 | ABCB1 (0.58) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL2790042 | 0.70 | MEN1 (0.68) | ABCB1USP2ATMALDH1A1KDM4E | |
| SCHEMBL20714286 | 0.70 | ALDH1A1 (0.51) | ABCB1USP2ATMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094536-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | Life Technologies Corporation (US) | 2009-07-30 | — | — | WO | disclosed |