Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070243 | 0.95 | L3MBTL1 (0.47) | L3MBTL1ABCB1PRMT5WDR77ABCC1 | |
| SCHEMBL6069752 | 0.85 | LTA4H (0.55) | LTA4HKDM4E | |
| SCHEMBL13898765 | 0.85 | PRMT5 (0.65) | PRMT5WDR77 | |
| SCHEMBL15833305 | 0.85 | PRMT5 (0.65) | PRMT5WDR77 | |
| SCHEMBL6070257 | 0.84 | BACE1 (0.56) | L3MBTL1LTA4HKDM4E | |
| SCHEMBL6069522 | 0.84 | BACE1 (0.56) | L3MBTL1LTA4HKDM4E | |
| SCHEMBL1377022 | 0.84 | BACE1 (0.56) | L3MBTL1LTA4HKDM4E | |
| Hydrochloric Acid SCHEMBL3896271 | 0.84 | PRMT5 (0.64) | PRMT5WDR77 | |
| SCHEMBL1377237 | 0.82 | LTA4H (0.47) | LTA4HMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6070752 | 0.81 | HRH3 (0.47) | LTA4HMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4717306-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| US-7091199-B1 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-15 | — | — | US | claimed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | claimed |
| JP-2003509431-A | — | — | 2003-03-11 | — | — | JP | claimed |
| EP-1216249-A2 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2002-06-26 | — | — | EP | claimed |
| WO-2001019832-A2 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| US-7091199-B1 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | disclosed |