Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IARS1 | P41252 | 4/20 | 0.84 |
| ▸ | SARS1 | P49591 | 3/20 | 0.84 |
| ▸ | MARS1 | P56192 | 2/20 | 0.79 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | TARS1 | P26639 | 2/20 | 0.68 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580149 | 1.00 | IARS1 (0.84) | IARS1SARS1MARS1CA1CA2 | |
| Alasa SCHEMBL21067643 | 0.87 | TARS1 (0.87) | IARS1SARS1MARS1TARS1LARS1 | |
| Alasa SCHEMBL4320823 | 0.87 | TARS1 (0.87) | IARS1SARS1MARS1TARS1LARS1 | |
| Alasa SCHEMBL29531843 | 0.87 | TARS1 (0.87) | IARS1SARS1MARS1TARS1LARS1 | |
| SCHEMBL29737838 | 0.84 | CA1 (1.00) | IARS1SARS1MARS1CA1CA2 | |
| SCHEMBL2489469 | 0.84 | CA1 (1.00) | IARS1SARS1MARS1CA1CA2 | |
| SCHEMBL2489474 | 0.84 | CA1 (1.00) | IARS1SARS1MARS1CA1CA2 | |
| SCHEMBL14201599 | 0.84 | CA1 (1.00) | IARS1SARS1MARS1CA1CA2 | |
| SCHEMBL21067691 | 0.81 | TARS1 (1.00) | IARS1SARS1MARS1TARS1LARS1 | |
| SCHEMBL4316150 | 0.81 | TARS1 (1.00) | IARS1SARS1MARS1TARS1LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | ACAT1, ACAT2, APEH | IARS1 2068/4885SARS1 722/4885MARS1 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.