Hydrochloric Acid

Hydrochloric Acid

SCHEMBL137748

CCCC1([Zr+2]C2(CCC)C=Cc3ccccc32)C=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7199015 0.90 KDM4E (0.36) KDM4EPKM
Hydrochloric Acid SCHEMBL7198460 0.89 KDM4E (0.35) KDM4EPKM
Hydrochloric Acid SCHEMBL7200977 0.87 MEN1 (0.36) KDM4EPKM
Hydrochloric Acid SCHEMBL7200904 0.87 MEN1 (0.36) KDM4EPKM
Hydrochloric Acid SCHEMBL7200935 0.86 OXTR (0.33) KDM4EPKM
Hydrochloric Acid SCHEMBL1685561 0.75
SCHEMBL23924806 0.74 KDM4E (0.38) KDM4EPKM
SCHEMBL17023010 0.74 KDM4E (0.35) KDM4EPKM
Hydrochloric Acid SCHEMBL137751 0.72 KDM4E (0.34) KDM4EPKM
SCHEMBL813298 0.71 KDM4E (0.36) KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2614095-B1 NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO (US) 2015-08-26 EP claimed
US-8932975-B2 Catalyst systems and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-01-13 US claimed
EP-2614095-A1 NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2013-07-17 EP claimed
WO-2012033670-A1 NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-03-15 WO claimed
US-20120059134-A1 Novel Catalyst Systems and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-03-08 US claimed
EP-3209723-B1 POLYMERS WITH IMPROVED PROCESSABILITY FOR PIPE APPLICATIONS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2020-05-13 EP disclosed
US-9994659-B2 Polymers with improved processability for pipe applications CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-06-12 US disclosed
US-20180044454-A1 Polymers with Improved Processability for Pipe Applications CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-02-15 US disclosed
US-9828451-B2 Polymers with improved processability for pipe applications CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-28 US disclosed
EP-3209723-A1 POLYMERS WITH IMPROVED PROCESSABILITY FOR PIPE APPLICATIONS Chevron Phillips Chemical Company LP (US) 2017-08-30 EP disclosed
EP-2751145-B1 POLYMER COMPOSITIONS HAVING IMPROVED BARRIER PROPERTIES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-07-19 EP disclosed
US-9637573-B2 Polymer compositions and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-05-02 US disclosed
EP-1412400-A2 MIXED METALLOCENE CATALYST SYSTEMS CONTAINING A POOR COMONOMER INCORPORATOR AND A GOOD COMONOMER INCORPORATOR Univation Technologies LLC (US) 2004-04-28 EP disclosed
US-20040077785-A1 Low comonomer incorporating metallocene catalyst compounds UNIVATION TECHNOLOGIES, LLC 2004-04-22 US disclosed
EP-0776909-B1 HIGH DENSITY ETHYLENE POLYMER AND METHOD FOR PRODUCING THE SAME ASAHI CHEMICAL IND (JP) 2003-11-19 EP disclosed
US-20030088038-A1 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator UNIVATION TECHNOLOGIES, LLC 2003-05-08 US disclosed
WO-2003008465-A2 LOW COMONOMER INCORPORATING METALLOCENE CATALYST COMPOUNDS UNIVATION TECHNOLOGIES, LLC (US) 2003-01-30 WO disclosed
WO-2003008468-A2 MIXED METALLOCENE CATALYST SYSTEMS CONTAINING A POOR COMONOMER INCORPORATOR AND A GOOD COMONOMER INCORPORATOR UNIVATION TECHNOLOGIES, LLC (US) 2003-01-30 WO disclosed
US-5973083-A HIGH IMPACT RESISTANCE AND HIGH STIFFNESS, EXCELLENT MOLDABILITY, HIGH MELT FLOWABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-10-26 US disclosed
EP-0776909-A1 HIGH-DENSITY ETHYLENIC POLYMER AND PROCESS FOR PRODUCING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-06-04 EP disclosed