Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023010 | 0.98 | KDM4E (0.35) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL7196705 | 0.90 | KDM4E (0.36) | KDM4EPKM | |
| SCHEMBL8854187 | 0.88 | KDM4E (0.36) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL7196712 | 0.86 | KDM4E (0.33) | KDM4EPKM | |
| SCHEMBL8854191 | 0.84 | KDM4E (0.33) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL6558666 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27948785 | 0.75 | KDM4E (0.36) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL6295905 | 0.75 | — | — | |
| SCHEMBL23924806 | 0.74 | KDM4E (0.38) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL8407495 | 0.74 | KDM4E (0.35) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614095-B1 | NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-08-26 | — | — | EP | claimed |
| US-8932975-B2 | Catalyst systems and methods of making and using same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-01-13 | — | — | US | claimed |
| US-20120059134-A1 | Novel Catalyst Systems and Methods of Making and Using Same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-08 | — | — | US | claimed |
| EP-3209723-B1 | POLYMERS WITH IMPROVED PROCESSABILITY FOR PIPE APPLICATIONS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2020-05-13 | — | — | EP | disclosed |
| US-9994659-B2 | Polymers with improved processability for pipe applications | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-06-12 | — | — | US | disclosed |
| US-20180044454-A1 | Polymers with Improved Processability for Pipe Applications | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2018-02-15 | — | — | US | disclosed |
| US-9828451-B2 | Polymers with improved processability for pipe applications | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-11-28 | — | — | US | disclosed |
| EP-3209723-A1 | POLYMERS WITH IMPROVED PROCESSABILITY FOR PIPE APPLICATIONS | Chevron Phillips Chemical Company LP (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2751145-B1 | POLYMER COMPOSITIONS HAVING IMPROVED BARRIER PROPERTIES | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9637573-B2 | Polymer compositions and methods of making and using same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-05-02 | — | — | US | disclosed |
| EP-2951213-B1 | CATALYST COMPOSITIONS, METHODS OF MAKING THEM AND THEIR USE | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2017-03-29 | — | — | EP | disclosed |
| US-20130059100-A1 | Polymer Compositions Having Improved Barrier Properties | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-03-07 | — | — | US | disclosed |
| WO-2012033670-A1 | NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-15 | — | — | WO | disclosed |
| US-20120059134-A1 | Novel Catalyst Systems and Methods of Making and Using Same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-08 | — | — | US | disclosed |
| US-7141632-B2 | Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator | UNIVATION TECHNOLOGIES, LLC (US) | 2006-11-28 | — | — | US | disclosed |
| US-7060765-B2 | Low comonomer incorporating metallocene catalyst compounds | UNIVATION TECHNOLOGIES, LLC (US) | 2006-06-13 | — | — | US | disclosed |
| US-6828394-B2 | Used for copolymerizing ethylene to form a copolymer having a bimodal molecular weight distribution | UNIVATION TECHNOLOGIES, LLC | 2004-12-07 | — | — | US | disclosed |
| US-20040225088-A1 | Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator | VAUGHAN GEORGE ALAN (US) | 2004-11-11 | — | — | US | disclosed |
| US-20040077785-A1 | Low comonomer incorporating metallocene catalyst compounds | UNIVATION TECHNOLOGIES, LLC | 2004-04-22 | — | — | US | disclosed |
| US-20030088038-A1 | Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator | UNIVATION TECHNOLOGIES, LLC | 2003-05-08 | — | — | US | disclosed |