⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13946865 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL18133939 | 0.79 | — | — | |
| SCHEMBL11025109 | 0.74 | LMNA (0.30) | — | |
| SCHEMBL11999101 | 0.73 | — | — | |
| SCHEMBL19104167 | 0.73 | — | — | |
| SCHEMBL19115298 | 0.69 | — | — | |
| SCHEMBL11999099 | 0.69 | — | — | |
| SCHEMBL19103687 | 0.65 | L3MBTL1 (0.39) | — | |
| SCHEMBL3057696 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL15961520 | 0.65 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192121-A1 | NOVEL BISAMIDATE PHOSPHONATE PRODRUGS | JIANG TAO | 2009-07-30 | — | — | US | disclosed |
| US-7563774-B2 | Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes | METABASIS THERAPEUTICS, INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-20080004226-A1 | Combination of FBPase Inhibitors and Insulin Sensitizers for the Treatment of Diabetes | METABASIS THERAPEUTICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |