Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243410 | 0.81 | KDM4E (0.76) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL2624544 | 0.81 | SMN1; SMN2 (0.77) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL16384055 | 0.79 | MAPT (0.70) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL13189376 | 0.79 | RAB9A (0.66) | RAB9ANPC1PKMKDM4ETP53 | |
| SCHEMBL10144065 | 0.79 | MAPT (0.77) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL14591818 | 0.78 | RAB9A (0.64) | RAB9ANPC1PKMKDM4ETP53 | |
| SCHEMBL10279091 | 0.78 | MAPT (0.75) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL23657588 | 0.78 | MAPT (0.84) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL2624542 | 0.78 | MAPT (1.00) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL5997449 | 0.78 | MAPT (0.74) | RAB9ANPC1KDM4ETP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | RAB9A 959/4885NPC1 1716/4885PKM 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.