Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picoperine SCHEMBL209959 | 0.99 | HRH3 (0.43) | HRH3MAPTSMN1; SMN2LIN28ATDP1 | |
| Picoperine SCHEMBL1651072 | 0.99 | HRH3 (0.43) | HRH3MAPTSMN1; SMN2LIN28ATDP1 | |
| Picoperine SCHEMBL9184091 | 0.99 | HRH3 (0.43) | HRH3MAPTSMN1; SMN2LIN28ATDP1 | |
| Histapyrrodine SCHEMBL1651354 | 0.79 | SIGMAR1 (0.51) | MAPTSMN1; SMN2ALDH1A1SIGMAR1LTA4H | |
| Histapyrrodine SCHEMBL142300 | 0.78 | SIGMAR1 (0.54) | MAPTSMN1; SMN2ALDH1A1SIGMAR1LTA4H | |
| SCHEMBL18157925 | 0.77 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2LIN28ATDP1ALDH1A1 | |
| SCHEMBL29777383 | 0.77 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2LIN28ATDP1ALDH1A1 | |
| Histapyrrodine SCHEMBL316865 | 0.77 | SIGMAR1 (0.53) | MAPTSMN1; SMN2ALDH1A1SIGMAR1LTA4H | |
| SCHEMBL3939455 | 0.75 | HRH3 (0.55) | HRH3ALDH1A1SIGMAR1 | |
| SCHEMBL14058727 | 0.75 | HRH3 (0.55) | HRH3ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887519-B1 | METHODS OF DETERMINING PH AND CALCIUM OR CHLORIDE CONCENTRATION IN SAMPLES | UNIV CHICAGO (US) | 2025-11-05 | — | — | EP | claimed |
| US-20250333746-A1 | RNA-NANOSTRUCTURED DOUBLE ROBOTS AND METHODS OF USE THEREOF | UNIV ARIZONA STATE (US) | 2025-10-30 | — | — | US | claimed |
| US-12436156-B2 | Methods of determining pH and calcium or chloride concentration in samples | THE UNIVERSITY OF CHICAGO (US) | 2025-10-07 | — | — | US | claimed |
| CN-118191045-A | Electrochemiluminescence detection method for malathion | 江西师范大学 | 2024-06-14 | — | — | CN | claimed |
| CN-117929334-A | Method for detecting alkaline phosphatase based on copper nanoclusters | 遵义医科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117538309-A | Electrochemiluminescence detection method for malathion | 江西师范大学 | 2024-02-09 | — | — | CN | claimed |
| CN-111650260-B | Electrochemical detection method for chicken infectious bronchitis virus NNA strain | 南京农业大学 | 2024-02-02 | — | — | CN | claimed |
| CN-114113271-B | Preparation method of photoelectrochemical organic transistor sensor for detecting pesticide malathion | 杭州富鼎检测有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-116411113-A | Transgenic component detection method based on CRISPR Cas enzyme gene editing technology | 中国热带农业科学院三亚研究院 | 2023-07-11 | — | — | CN | claimed |
| CN-114675038-B | Thermal fluorescence analysis and detection method and kit for protein content | 陕西科技大学 | 2023-02-10 | — | — | CN | claimed |
| US-20020151525-A1 | Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation | COLLINS DOUGLAS A (US) | 2002-10-17 | — | — | US | claimed |
| WO-2002055530-A2 | TRANSCOBALAMIN BINDING CONJUGATES USEFUL FOR TREATING ABNORMAL CELLULAR PROLIFERATION | MAYO FOUNDATION (US) | 2002-07-18 | — | — | WO | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| CN-1281048-A | Reconstituted human t-PA molecule and its engineering bacterium strain to express it | UNIV WUHAN (CN) | 2001-01-24 | — | — | CN | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-0440009-B1 | DEVICE AND METHOD FOR THE MODULATED COOLING OF A MOVING CYLINDRICAL OBJECT | CENTRE DE RECHERCHES METALLURGIQUES CENTRUM VOOR RESEARCH IN DE METALLURGIE Association sans but lucratif (BE) | 1993-09-29 | — | — | EP | claimed |
| EP-0245456-A4 | AIDS VIRUS GENE EXPRESSION. | US COMMERCE (US) | 1989-01-24 | — | — | EP | claimed |
| EP-0245456-A1 | AIDS VIRUS GENE EXPRESSION | THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE (US) | 1987-11-19 | — | — | EP | claimed |
| WO-1987002989-A1 | AIDS VIRUS GENE EXPRESSION | UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) | 1987-05-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151525-A1 | Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation | PCNA, MKI67, SLC19A1 | HRH3 2620/4885MAPT 2973/4885SMN1; SMN2 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.