SCHEMBL18157925

SCHEMBL18157925

c1ccc(N(Cc2ccccn2)Cc2ccccn2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.59
MAPT P10636 1/20 0.59
LIN28A Q9H9Z2 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
KCNA5 P22460 2/20 0.53
KMT2A Q03164 1/20 0.51
NR1H2 P55055 2/20 0.50
NR1H3 Q13133 2/20 0.50
KCNN4 O15554 1/20 0.49
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
HRH1 P35367 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
CHRNA7 P36544 2/20 0.44
LMNA P02545 1/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777383 1.00 SMN1; SMN2 (0.59) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL30097972 0.85 L3MBTL1 (0.54) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL15489522 0.85 CYP2C19 (0.55) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL17495247 0.85 L3MBTL1 (0.54) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL4370206 0.83 MAPT (0.59) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL10502045 0.83 HRH1 (0.50) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL10994612 0.82 CXCR3 (0.53) SMN1; SMN2MAPTLIN28ATDP1KMT2A
SCHEMBL30977271 0.81 ALDH1A1 (0.56) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL5050849 0.81 ALDH1A1 (0.50) SMN1; SMN2MAPTLIN28ATDP1KCNA5
SCHEMBL16000559 0.81 NR1H2 (0.59) SMN1; SMN2MAPTLIN28ATDP1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206762-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-06-26 US disclosed
WO-2023192348-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-10-05 WO disclosed
WO-2023192348-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-10-05 WO disclosed
US-20190144924-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2019-05-16 US disclosed
US-20190144924-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2019-05-16 US disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-10167397-B2 Method to determine connector metal wear via fluorescence INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-01-01 US disclosed
EP-3374520-A1 BIOSENSORS Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2018-09-19 EP disclosed
US-20180095038-A1 METHOD TO DETERMINE CONNECTOR METAL WEAR VIA FLOURESENCE INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-9885659-B1 Method to determine connector metal wear via flouresence INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-02-06 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
WO-2017081684-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-05-18 WO disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206762-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS OPRM1, TRPA1, ICMT SMN1; SMN2 4178/4885MAPT 2206/4885LIN28A 1064/4885
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 SMN1; SMN2 2133/4885MAPT 97/4885LIN28A 2887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.