Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911142 | 0.89 | KMT2A (0.74) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL9334268 | 0.87 | KMT2A (0.80) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL13077932 | 0.86 | KMT2A (0.57) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL9911140 | 0.85 | KMT2A (0.68) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL9911141 | 0.85 | KMT2A (0.68) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL14438597 | 0.81 | CYP1A2 (0.49) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL28571050 | 0.81 | KMT2A (0.67) | KMT2AMEN1MTNR1AKDM4EHPGD | |
| SCHEMBL498807 | 0.81 | KMT2A (0.71) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL2177707 | 0.80 | MEN1 (0.47) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL10905518 | 0.78 | KMT2A (0.77) | KMT2AMEN1MTNR1AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9572891-B2 | Oligonucleotide conjugates | GERON CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| US-20150374841-A1 | Oligonucleotide Conjugates | GERON CORPORATION | 2015-12-31 | — | — | US | disclosed |
| US-9072790-B2 | Oligonucleotide conjugates | GERON CORPORATION (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130253042-A1 | Oligonucleotide Conjugates | GERON CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| EP-2114462-B1 | Compounds for fluorescence imaging | UNIV GENEVE (CH) | 2013-06-05 | — | — | EP | disclosed |
| US-8440635-B2 | Oligonucleotide conjugates | GERON CORPORATION (US) | 2013-05-14 | — | — | US | disclosed |
| US-7563618-B2 | Oligonucleotide conjugates | GERON CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374841-A1 | Oligonucleotide Conjugates | TERT, RNGTT, TRDMT1 | KMT2A 640/4885MEN1 2881/4885MTNR1A 2056/4885 |
| US-20130253042-A1 | Oligonucleotide Conjugates | TERT, RNGTT, TRDMT1 | KMT2A 640/4885MEN1 2881/4885MTNR1A 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.