Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.67 |
| ▸ | CTSL | P07711 | 15/20 | 0.67 |
| ▸ | CTSS | P25774 | 15/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784229 | 0.85 | CTSK (0.55) | CTSKCTSLCTSS | |
| SCHEMBL13784228 | 0.82 | CTSS (0.46) | CTSKCTSLCTSS | |
| SCHEMBL6841469 | 0.80 | CTSK (1.00) | CTSKCTSLCTSS | |
| SCHEMBL6073041 | 0.77 | CTSK (0.57) | CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL4314512 | 0.76 | CTSK (0.38) | CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL5983254 | 0.75 | CTSK (0.58) | CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL5983535 | 0.75 | CTSK (0.58) | CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL13784230 | 0.73 | CTSK (0.68) | CTSKCTSLCTSS | |
| SCHEMBL6072824 | 0.73 | CTSK (0.77) | CTSKCTSLCTSS | |
| SCHEMBL8337747 | 0.73 | CTSK (0.77) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |