Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.46 |
| ▸ | CTSL | P07711 | 14/20 | 0.46 |
| ▸ | CTSK | P43235 | 11/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784227 | 0.82 | CTSK (0.67) | CTSSCTSLCTSK | |
| SCHEMBL6842086 | 0.80 | CTSK (0.74) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL13784229 | 0.79 | CTSK (0.55) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL4314512 | 0.76 | CTSK (0.38) | CTSSCTSLCTSK | |
| SCHEMBL7148228 | 0.73 | CTSK (0.51) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL7015060 | 0.73 | CTSK (0.57) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL7013531 | 0.72 | CTSK (0.40) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL5532498 | 0.72 | CTSL (0.74) | CTSSCTSLCTSKCTSBGRN | |
| SCHEMBL6212781 | 0.70 | CTSK (0.33) | CTSSCTSLCTSK | |
| SCHEMBL6842065 | 0.68 | CTSK (0.56) | CTSSCTSLCTSKCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |