Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.43 |
| ▸ | CHRNG | P07510 | 4/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.43 |
| ▸ | CHRND | Q07001 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19339331 | 0.87 | GAA (0.47) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL12013627 | 0.87 | ACHE (0.50) | GAAACHEKMT2AHSD17B10ATM | |
| SCHEMBL7945435 | 0.84 | GAA (0.59) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL13313738 | 0.81 | GAA (0.42) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL16331984 | 0.79 | CA12 (0.50) | GAAKDM4ERECQLACHEALDH1A1 | |
| SCHEMBL10050728 | 0.77 | GAA (0.52) | GAAKDM4EDBHRECQLALDH1A1 | |
| SCHEMBL317796 | 0.77 | CA12 (0.52) | GAAKDM4EDBHRECQLALDH1A1 | |
| SCHEMBL12948133 | 0.77 | GAA (0.41) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL22989413 | 0.77 | KDM4E (0.41) | GAAKDM4EDBHRECQLSLC6A2 | |
| SCHEMBL10944943 | 0.76 | CES2 (0.46) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813608-B1 | Preparation of alpha-hydroxy ketones | CIBA HOLDING INC (CH) | 2009-07-29 | — | — | EP | disclosed |