Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.44 |
| ▸ | CHRNG | P07510 | 2/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRND | Q07001 | 2/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169278 | 0.87 | ACHE (0.44) | GAAACHESLC6A2SLC6A3CHRNA1 | |
| SCHEMBL13785367 | 0.87 | GAA (0.46) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL7945435 | 0.86 | GAA (0.59) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL10031819 | 0.86 | ACHE (0.52) | ACHEALOX5NPSR1ATMTDP1 | |
| SCHEMBL21099979 | 0.86 | ACHE (0.42) | GAAACHESLC6A2SLC6A3CHRNA1 | |
| SCHEMBL22753517 | 0.84 | GAA (0.44) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL13313738 | 0.83 | GAA (0.42) | GAAKDM4EDBHRECQLACHE | |
| SCHEMBL16683783 | 0.80 | KDM4E (0.48) | GAAKDM4EDBHRECQLSLC6A2 | |
| SCHEMBL317796 | 0.79 | CA12 (0.52) | GAAKDM4EDBHRECQLALDH1A1 | |
| SCHEMBL10050728 | 0.79 | GAA (0.52) | GAAKDM4EDBHRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310551-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME LLC (US) | 2023-10-05 | — | — | US | disclosed |
| EP-3789426-A1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | The Boeing Company (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3216820-B1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | BOEING CO (US) | 2020-09-23 | — | — | EP | disclosed |
| US-10689430-B2 | Insulin receptor partial agonists | MERCK SHARP & DOHME CORP. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20200062905-A1 | POLYARYLETHER KETONE IMIDE ADHESIVES | THE BOEING COMPANY | 2020-02-27 | — | — | US | disclosed |
| US-10465046-B2 | Polyarylether ketone imide adhesives | THE BOEING COMPANY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190177393-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-06-13 | — | — | US | disclosed |
| US-10011685-B2 | Polyarylether ketone imide adhesives | THE BOEING COMPANY (US) | 2018-07-03 | — | — | US | disclosed |
| US-9976063-B2 | Polyarylether ketone imide sulfone adhesives | THE BOEING COMPANY (US) | 2018-05-22 | — | — | US | disclosed |
| US-20170260432-A1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | THE BOEING COMPANY | 2017-09-14 | — | — | US | disclosed |
| US-20170260332-A1 | POLYARYLETHER KETONE IMIDE ADHESIVES | THE BOEING COMPANY | 2017-09-14 | — | — | US | disclosed |
| EP-3216820-A1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | The Boeing Company (US) | 2017-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177393-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | GAA 4062/4885KDM4E 4815/4885DBH 2640/4885 |
| US-10689430-B2 | Insulin receptor partial agonists | INSR, GPR119, IRS1 | GAA 4062/4885KDM4E 4815/4885DBH 2640/4885 |
| US-20230310551-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | GAA 4062/4885KDM4E 4815/4885DBH 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.