Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13786 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2DPP4POLB | |
| SCHEMBL4933350 | 0.79 | — | — | |
| SCHEMBL4087556 | 0.77 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4440625 | 0.77 | — | — | |
| SCHEMBL27949 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18496092 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2DPP4POLB | |
| SCHEMBL29140220 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2DPP4POLB | |
| SCHEMBL4952774 | 0.71 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL569156 | 0.69 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2DPP4POLB | |
| SCHEMBL17841720 | 0.68 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2DPP4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453804-A2 | CCR-3 RECEPTOR ANTAGONISTS VII | F. Hoffmann-La Roche AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003045917-A2 | CCR-3 RECEPTOR ANTAGONISTS VII | F. HOFFMANN-LAROCHE AG (CH) | 2003-06-05 | — | — | WO | disclosed |