Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109583 | 0.95 | POLB (0.59) | POLBGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL4954488 | 0.93 | POLB (0.58) | POLBGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL38658697 | 0.91 | POLB (0.51) | POLBGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4449787 | 0.83 | LMNA (0.50) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL38656601 | 0.82 | KLK5 (0.46) | POLBGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11668917 | 0.79 | LMNA (0.49) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2027079 | 0.79 | POLB (0.85) | POLBGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL10671305 | 0.79 | KMT2A (0.62) | POLBMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL656655 | 0.77 | POLB (0.97) | POLBGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL4729692 | 0.76 | MEN1 (0.49) | POLBGAAMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557102-B2 | Pyrazolidine-1,2-dicarboxyldiphenylamide derivatives as coagulation factor Xa inhibitors for the treatment of thromboses | MERCK PATENT GMBH (DE) | 2009-07-07 | — | — | US | disclosed |