Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954488 | 0.83 | POLB (0.58) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL830749 | 0.81 | RAB9A (0.64) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL6109583 | 0.81 | POLB (0.59) | KMT2AMAPTPOLBNPC1RAB9A | |
| SCHEMBL6852416 | 0.80 | KDM4E (0.62) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL5956401 | 0.79 | POLB (0.66) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5492077 | 0.78 | POLB (0.68) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL13787488 | 0.76 | POLB (0.61) | MAPTPOLBNPC1RAB9AKDM4E | |
| SCHEMBL9188898 | 0.76 | FAAH (0.62) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL11668917 | 0.76 | LMNA (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10671305 | 0.76 | KMT2A (0.62) | MEN1KMT2AMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | claimed |
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |