Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449787 | 0.95 | LMNA (0.50) | LMNANPC1RAB9ATDP1MAPT | |
| SCHEMBL10671305 | 0.84 | KMT2A (0.62) | NPC1RAB9ATDP1MAPTTP53 | |
| SCHEMBL6109583 | 0.84 | POLB (0.59) | LMNANPC1RAB9AMAPTTP53 | |
| SCHEMBL9764217 | 0.83 | SMN1; SMN2 (0.62) | LMNANPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL4954488 | 0.83 | POLB (0.58) | LMNANPC1RAB9AMAPTTP53 | |
| SCHEMBL13787488 | 0.79 | POLB (0.61) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL10596224 | 0.78 | MAPT (0.69) | LMNANPC1RAB9ATDP1MAPT | |
| SCHEMBL654537 | 0.78 | POLB (0.69) | LMNANPC1RAB9ATDP1MAPT | |
| SCHEMBL38658697 | 0.77 | POLB (0.51) | LMNANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13234925 | 0.77 | RAB9A (0.70) | LMNANPC1RAB9ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52113961-A | — | — | None | — | — | JP | disclosed |
| JP-S52113961-A | 1,2-ALKYLENE-1-ARYLTHIOCARBAMOYLHYDRAZINES | MITSUBISHI CHEM IND LTD | 1977-09-24 | — | — | JP | disclosed |