Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127441 | 0.82 | AHCY (0.54) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9130295 | 0.82 | AHCY (0.54) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9127438 | 0.82 | AHCY (0.54) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL13788539 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9127103 | 0.81 | LMNA (0.52) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9127110 | 0.81 | LMNA (0.52) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9128473 | 0.81 | LMNA (0.51) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9128480 | 0.81 | LMNA (0.51) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL9826496 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPK1ALBCYP1A2 | |
| SCHEMBL23620769 | 0.80 | PNP (0.58) | LMNASMN1; SMN2PNPTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090169507-A1 | PURINE NUCLEOSIDE ANALOGUES FOR TREATING FLAVIVIRIDAE INCLUDING HEPATITIS C | IDENIX PHARMACEUTICALS, INC. (US) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169507-A1 | PURINE NUCLEOSIDE ANALOGUES FOR TREATING FLAVIVIRIDAE INCLUDING HEPATITIS C | PNP, TPMT, MTAP | ALDH1A1 1160/4885LMNA 2831/4885MAPK1 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.