Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14937443 | 0.86 | DRD2 (0.49) | ALDH1A1TDP1L3MBTL1KMT2ADRD2 | |
| SCHEMBL13224665 | 0.84 | TSHR (0.56) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL5172812 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL1592876 | 0.82 | TDP1 (0.60) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL21118395 | 0.81 | TSHR (0.57) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL11235809 | 0.81 | NCF1 (0.46) | ALDH1A1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL16942933 | 0.80 | TSHR (0.44) | ALDH1A1MAPTKDM4ETDP1HPGD | |
| SCHEMBL11691609 | 0.80 | TSHR (0.44) | ALDH1A1MAPTKDM4ETDP1HPGD | |
| SCHEMBL11687770 | 0.80 | KDM4E (0.51) | ALDH1A1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL20496732 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181364-A1 | ZINC BINDING COMPOUNDS AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |