Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13789687 | 0.80 | POLB (0.51) | KCNMA1POLBKDM4EMAPTXBP1 | |
| SCHEMBL9876678 | 0.70 | PTGER1 (0.53) | POLBKDM4EMAPTXBP1MAPK1 | |
| SCHEMBL11853749 | 0.68 | KCNMA1 (0.61) | KCNMA1KDM4EMAPTHTTGAA | |
| Biphenyl SCHEMBL28254465 | 0.64 | TSHR (0.81) | KDM4EMAPTHTTGAAMMP2 | |
| SCHEMBL17112234 | 0.64 | SMN1; SMN2 (0.42) | MAOBPOLBKDM4EMAPTMAPK1 | |
| SCHEMBL4392334 | 0.64 | COMT (0.71) | KDM4EMAPTXBP1HTTGAA | |
| SCHEMBL2179670 | 0.64 | ALDH1A1 (0.49) | POLBKDM4EMAPTXBP1MAPK1 | |
| SCHEMBL9764609 | 0.64 | KDM4E (0.43) | MAOBKDM4EHTTADORA3LMNA | |
| Biphenyl SCHEMBL28225215 | 0.63 | TSHR (0.78) | KDM4EMAPTHTTGAAMMP2 | |
| SCHEMBL28139129 | 0.63 | POLB (0.62) | KCNMA1POLBKDM4EMAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560174-B2 | Imidazole or imidazopyridine derivatives are the phosphorescent material in the luminescent layer between electrodes | FUJIFILM CORPORATION (JP) | 2009-07-14 | — | — | US | disclosed |