Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752394 | 0.77 | MPO (0.51) | KDM4ENPC1RAB9AKDM4CHTT | |
| SCHEMBL17112234 | 0.76 | SMN1; SMN2 (0.42) | KDM4EMEN1NPC1RAB9AKMT2A | |
| Quinoline SCHEMBL28265466 | 0.66 | ALDH1A1 (0.49) | KDM4ENPC1RAB9AHTTHIF1A | |
| SCHEMBL13789733 | 0.64 | MAOB (0.43) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL23726655 | 0.64 | KDM4E (0.37) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL16896248 | 0.64 | KDM4C (0.49) | KDM4ENPC1RAB9AKDM4CHTT | |
| SCHEMBL15245369 | 0.62 | NPC1 (0.46) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL11851657 | 0.61 | KDM4E (0.50) | KDM4ENPC1IDO1RAB9AL3MBTL1 | |
| SCHEMBL9168570 | 0.61 | NPSR1 (0.56) | KDM4ENPSR1L3MBTL1HTTLMNA | |
| SCHEMBL700910 | 0.60 | KDM4E (1.00) | KDM4EMEN1NPC1HSP90AA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994453-A | Treating asthma, diabetes, obesity, immunosuppression | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |