Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18714363 | 1.00 | CYP2C19 (0.50) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL2604878 | 0.82 | CYP2C19 (0.50) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL15257158 | 0.79 | CYP2D6 (0.52) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL7441355 | 0.78 | CYP2D6 (0.46) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL10444397 | 0.78 | CYP2D6 (0.46) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL30997680 | 0.78 | ANPEP (0.62) | ANPEPDNPEPLMNA | |
| SCHEMBL23866601 | 0.78 | CYP2D6 (0.56) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL2315958 | 0.78 | CYP2D6 (0.56) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL8633406 | 0.78 | CYP2D6 (0.56) | CYP2C19CYP2D6MAPTMMP1MMP8 | |
| SCHEMBL13789959 | 0.77 | SLC7A5 (0.54) | CYP2C19CYP2D6MAPTMMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114870-B1 | SYNTHETIC ION CHANNELS | VERSITECH LTD (CN) | 2019-07-03 | — | — | EP | disclosed |
| US-9610263-B2 | Method of modulating membrane potential of a cell | VERSITECH LIMITED (CN) | 2017-04-04 | — | — | US | disclosed |
| US-9610263-B2 | Method of modulating membrane potential of a cell | VERSITECH LIMITED (CN) | 2017-04-04 | — | — | US | disclosed |
| US-9162977-B2 | Synthetic ion channels | THE UNIVERSITY OF HONG KONG (CN) | 2015-10-20 | — | — | US | disclosed |
| US-9162977-B2 | Synthetic ion channels | THE UNIVERSITY OF HONG KONG (CN) | 2015-10-20 | — | — | US | disclosed |
| US-20130244944-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2013-09-19 | — | — | US | disclosed |
| US-20130244944-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2013-09-19 | — | — | US | disclosed |
| US-8378138-B2 | self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. | The University of Hong Kong & Versitech Limited (CN) | 2013-02-19 | — | — | US | disclosed |
| US-8378138-B2 | self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. | The University of Hong Kong & Versitech Limited (CN) | 2013-02-19 | — | — | US | disclosed |
| US-20090163595-A1 | Method of Modulating Membrane Potential of a Cell | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2009-06-25 | — | — | US | disclosed |
| US-20090163595-A1 | Method of Modulating Membrane Potential of a Cell | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2009-06-25 | — | — | US | disclosed |
| US-20080146513-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2008-06-19 | — | — | US | disclosed |
| US-20080146513-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244944-A1 | Synthetic Ion Channels | KCNJ2, KCNJ1, KCNN2 | CYP2C19 4847/4885CYP2D6 4795/4885MAPT 2294/4885 |
| US-20080146513-A1 | Synthetic Ion Channels | KCNJ2, KCNJ1, KCNN2 | CYP2C19 4847/4885CYP2D6 4795/4885MAPT 2294/4885 |
| US-20090163595-A1 | Method of Modulating Membrane Potential of a Cell | VDAC1, ATP2A3, ATP2A2 | CYP2C19 4864/4885CYP2D6 4820/4885MAPT 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.