Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | POLA1 | P09884 | 1/20 | 0.74 |
| ▸ | POLD1 | P28340 | 1/20 | 0.74 |
| ▸ | TK1 | P04183 | 4/20 | 0.63 |
| ▸ | DTYMK | P23919 | 4/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Telbivudine 5'Triphosphate SCHEMBL29725270 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL1579556 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL77831 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL18785124 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL11055949 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| SCHEMBL887725 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL14279191 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| SCHEMBL21682516 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL21275938 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK | |
| Deoxythymidine_Triphosphate SCHEMBL18844514 | 0.90 | POLB (0.78) | POLBPOLA1POLD1TK1DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550442-B2 | For therapy of subject infected with a retrovirus | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-06-23 | — | — | US | disclosed |