Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | POLA1 | P09884 | 1/20 | 0.74 |
| ▸ | POLD1 | P28340 | 1/20 | 0.74 |
| ▸ | DTYMK | P23919 | 4/20 | 0.65 |
| ▸ | TYMS | P04818 | 1/20 | 0.65 |
| ▸ | TK1 | P04183 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxythymidine_Triphosphate SCHEMBL77832 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Telbivudine 5'Triphosphate SCHEMBL29725270 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL11055949 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| SCHEMBL887725 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL14279191 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL18785124 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL77831 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL1579556 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL21275938 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| SCHEMBL21682516 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548909-B2 | Methods of using nucleotide analogues | IsoPlexis Corporation (US) | 2023-01-10 | — | — | US | disclosed |
| US-20170211134-A1 | THIOL-CONTAINING CLEAVE REAGENTS AND OXIDATIVE WASH | IsoPlexis Corporation | 2017-07-27 | — | — | US | disclosed |
| US-20170137878-A1 | METHODS OF USING NUCLEOTIDE ANALOGUES | IsoPlexis Corporation | 2017-05-18 | — | — | US | disclosed |
| US-20170137869-A1 | METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS | IsoPlexis Corporation | 2017-05-18 | — | — | US | disclosed |
| US-20170130051-A1 | NUCLEOTIDE ANALOGUES | IsoPlexis Corporation | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548909-B2 | Methods of using nucleotide analogues | NT5C3B, SAMHD1, RNGTT | POLB 32/4885POLA1 216/4885POLD1 136/4885 |
| US-20170137869-A1 | METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS | RNGTT, NT5C3B, DUT | POLB 51/4885POLA1 300/4885POLD1 185/4885 |
| US-20170130051-A1 | NUCLEOTIDE ANALOGUES | NT5C3B, SAMHD1, DUT | POLB 28/4885POLA1 171/4885POLD1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.