Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18437163 | 0.69 | HDAC8 (0.31) | — | |
| SCHEMBL102449 | 0.67 | RAB9A (0.41) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL9826359 | 0.67 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1201661 | 0.67 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL220022 | 0.67 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL678452 | 0.67 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL498897 | 0.66 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL2710465 | 0.65 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL5965223 | 0.65 | NPC1 (0.42) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL500400 | 0.65 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189361-A | Estrogen receptor modulators and use thereof | ARAGON PHARMACEUTICALS INC | 2013-07-03 | — | — | CN | claimed |
| CN-102665414-A | Plant disease control composition and method for controlling plant disease using same | MITSUI CHEMICALS AGRO INC | 2012-09-12 | — | — | CN | claimed |
| CN-102652129-A | Amino oxazine derivatives | HOFFMANN LA ROCHE | 2012-08-29 | — | — | CN | claimed |
| CN-102020698-B | Hepatitis C virus protease inhibitors | TAIGEN BIOTECHNOLOGY CO LTD | 2012-08-29 | — | — | CN | claimed |
| CN-102341371-A | As LTC4Bis-aromatic compounds as synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-01 | — | — | CN | claimed |
| JP-4660199-B2 | — | — | 2011-03-30 | — | — | JP | claimed |
| CN-101133064-B | Substituted oxa-diaza-spiro-[5.5]-undecanone derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | claimed |
| CN-101137657-B | Diaza-spiro- [4.4] -nonane derivatives as neurokinin (NK1) antagonists | JANSSEN PHARMACEUTICA NV | 2011-02-02 | — | — | CN | claimed |
| CN-100591682-C | Substituted diaza-spiro-[4.5|-decane derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA NV | 2010-02-24 | — | — | CN | claimed |
| CN-100584843-C | Substituted diaza-spiro-[5.5|-undecane derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA NV | 2010-01-27 | — | — | CN | claimed |
| CN-1384830-A | Novel spiroheterocyclic compounds as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMA (US) | 2002-12-11 | — | — | CN | claimed |
| CN-1079639-C | Selective herbicides based on aryluracils | BAYER AG (DE) | 2002-02-27 | — | — | CN | claimed |
| CN-1305466-A | Substituted phenyl pyridazinones | BAYER AG (DE) | 2001-07-25 | — | — | CN | claimed |
| CN-1261345-A | Glyoxylic acid amides | BAYER AG (DE) | 2000-07-26 | — | — | CN | claimed |
| CN-1216043-A | Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors | SEARLE & CO (US) | 1999-05-05 | — | — | CN | claimed |
| CN-1095591-A | The associating of a kind of cholesteral biosynthesis inhibitor and a kind of beta-lactam cholesterol absorption inhibitor | SCHERING CORP (US) | 1994-11-30 | — | — | CN | claimed |
| CN-1069024-A | As 'beta '-lactam compounds that reduces the replacement of cholesterol medicament in the blood and preparation method thereof | SCHERING CORP (US) | 1993-02-17 | — | — | CN | claimed |
| US-4980348-A | HETEROANELLATED PHENYLGLYCINE-BETA-LACTAM ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| CN-88103202-A | Vinyl cephalosporin compound that replaces and preparation method thereof and as the application of medicine | — | 1988-12-21 | — | — | CN | claimed |
| US-4147789-A | ANTIPARKINSON AGENTS | SANDOZ LTD. (CH) | 1979-04-03 | — | — | US | claimed |