Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135899 | 0.69 | KDM4E (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17967465 | 0.69 | GPR35 (0.35) | ALDH1A1GAA | |
| SCHEMBL9826359 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL498897 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12608094 | 0.67 | MEN1 (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1379282 | 0.67 | KDM4E (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3612098 | 0.67 | — | — | |
| SCHEMBL3545 | 0.67 | L3MBTL1 (0.57) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16291133 | 0.67 | L3MBTL1 (0.57) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13977912 | 0.66 | KDM4E (0.52) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402125-A | Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof | 南京林业大学 | 2024-01-16 | — | — | CN | claimed |
| US-9018214-B2 | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LIMITED (GB) | 2015-04-28 | — | — | US | claimed |
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | claimed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | claimed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | claimed |
| CN-119842165-A | Method for preparing exterior wall flame-retardant material from waste plastics | 东莞市众一新材料科技有限公司 | 2025-04-18 | — | — | CN | disclosed |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | US | disclosed |
| CN-116289210-B | Bath towel with strong water absorbability and preparation method thereof | 江苏南星家纺有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117402125-A | Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof | 南京林业大学 | 2024-01-16 | — | — | CN | disclosed |
| US-11866428-B2 | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LIMITED (GB) | 2024-01-09 | — | — | US | disclosed |
| CN-116289210-A | Bath towel with strong water absorbability and preparation method thereof | 江苏南星家纺有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20210122749-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2021-04-29 | — | — | US | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |
| US-4138556-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-4130644-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |
| US-4126682-A | 7-ACYL-3-(CARBOXYALKYL AND CARBAMOYLALKYL SUBSTITUTED OXADIAZOLYLTHIOMETHYL) CEPHALOSPORINS AND ANTIBACTERIAL COMPOSITIONS AND METHODS EMPLOYING THEM | SMITHKLINE CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112088-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4067880-A | SULFOALKYL-OXADIAZOLE THIOLS | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4041162-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4034092-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | KDM4E 2541/4885ALDH1A1 1493/4885HPGD 754/4885 |
| US-20210122749-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | KDM4E 2541/4885ALDH1A1 1493/4885HPGD 754/4885 |
| US-11866428-B2 | Bicyclic heterocycle compounds and their uses in therapy | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | KDM4E 2541/4885ALDH1A1 1493/4885HPGD 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.