Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589944 | 0.98 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL12634021 | 0.93 | ALDH1A1 (0.40) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL12812532 | 0.80 | LMNA (0.53) | TSHRALDH1A1SMN1; SMN2POLBUSP2 | |
| SCHEMBL22627043 | 0.78 | POLB (0.58) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL1984161 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL12874013 | 0.77 | ALDH1A1 (0.47) | TSHRALDH1A1SMN1; SMN2POLBUSP2 | |
| SCHEMBL3611548 | 0.77 | TSHR (0.49) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL10085632 | 0.77 | SMN1; SMN2 (0.50) | TSHRALDH1A1SMN1; SMN2POLBUSP2 | |
| SCHEMBL364306 | 0.77 | POLB (0.46) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL365996 | 0.77 | TSHR (0.49) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074812-A1 | ANTIBACTERIAL CONDENSED THIAZOLES | PROLYSIS LTD (GB) | 2009-06-18 | — | — | WO | disclosed |