Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.35 |
| ▸ | CASP5 | P51878 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13798271 | 0.98 | TSHR (0.45) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL12634021 | 0.95 | ALDH1A1 (0.40) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL12812532 | 0.82 | LMNA (0.53) | ALDH1A1TSHRPOLBSMN1; SMN2USP2 | |
| SCHEMBL22627043 | 0.80 | POLB (0.58) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL20244719 | 0.79 | POLB (0.36) | ALDH1A1TSHRPOLBSMN1; SMN2USP2 | |
| SCHEMBL24126297 | 0.76 | SIGMAR1 (0.46) | KDM4E | |
| SCHEMBL2900843 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL1433020 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL15952948 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL29656701 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPK1TSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019234243-A1 | NOVEL COMPOUNDS FOR DIAGNOSIS | AC IMMUNE SA (CH) | 2019-12-12 | — | — | WO | disclosed |