Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382785 | 0.93 | F10 (0.49) | F10GAACA12CA1CA2 | |
| SCHEMBL1379979 | 0.88 | F10 (0.47) | F10CA12CA1CA2CA9 | |
| SCHEMBL1377941 | 0.87 | CA1 (0.48) | F10CA12CA1CA2CA9 | |
| SCHEMBL6525810 | 0.82 | MAPT (0.57) | F10GAAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8325725 | 0.81 | MAPT (0.55) | F10KDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL5428908 | 0.80 | F10 (0.60) | F10L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28626654 | 0.79 | MAPT (0.56) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL221944 | 0.78 | F10 (0.48) | F10GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22353066 | 0.75 | MEN1 (0.52) | F10GAAKDM4EALDH1A1MEN1 | |
| SCHEMBL1378839 | 0.75 | F10 (0.45) | F10GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| JP-4699985-B2 | — | — | 2011-06-15 | — | — | JP | claimed |
| JP-2006512321-A | — | — | 2006-04-13 | — | — | JP | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | claimed |