Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525810 | 0.86 | MAPT (0.57) | MEN1KMT2ALMNAPOLBF10 | |
| SCHEMBL221944 | 0.79 | F10 (0.48) | MEN1KMT2ALMNAF10MAPT | |
| SCHEMBL223375 | 0.78 | TSHR (0.56) | MEN1KMT2APOLBF10CYP2D6 | |
| SCHEMBL8325725 | 0.76 | MAPT (0.55) | MEN1KMT2AF10CYP1A2CYP2C19 | |
| SCHEMBL5428908 | 0.76 | F10 (0.60) | MEN1KMT2ALMNAPOLBF10 | |
| SCHEMBL1379938 | 0.75 | F10 (0.51) | MEN1KMT2AF10KDM4EGAA | |
| SCHEMBL1379979 | 0.74 | F10 (0.47) | KMT2ALMNAF10MAPTKDM4E | |
| SCHEMBL1382785 | 0.73 | F10 (0.49) | MEN1KMT2AF10KDM4EGAA | |
| SCHEMBL1377941 | 0.73 | CA1 (0.48) | MEN1KMT2AF10 | |
| SCHEMBL28690666 | 0.72 | TDP1 (0.52) | MEN1KMT2ALMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |