Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221944 | 0.86 | F10 (0.48) | MAPTGAARAB9AALDH1A1HPGD | |
| SCHEMBL22353066 | 0.86 | MEN1 (0.52) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL223375 | 0.85 | TSHR (0.56) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8325725 | 0.83 | MAPT (0.55) | MAPTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL5428908 | 0.82 | F10 (0.60) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL1379938 | 0.82 | F10 (0.51) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1379979 | 0.80 | F10 (0.47) | MAPTALDH1A1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1382785 | 0.80 | F10 (0.49) | GAAALDH1A1MEN1KMT2ANAMPT | |
| SCHEMBL1377941 | 0.79 | CA1 (0.48) | MEN1KMT2AF10TSHRCASP7 | |
| SCHEMBL1379531 | 0.78 | F10 (0.52) | MAPTGAARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585730-A1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004065369-A1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2004-08-05 | — | — | WO | disclosed |