Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379938 | 0.93 | F10 (0.51) | F10KDM4EGAAKMT2AMEN1 | |
| SCHEMBL1379979 | 0.84 | F10 (0.47) | F10KDM4EKMT2AALDH1A1CA12 | |
| SCHEMBL1377941 | 0.82 | CA1 (0.48) | F10KMT2AMEN1CA12CA1 | |
| SCHEMBL1378839 | 0.82 | F10 (0.45) | F10KDM4EGAAKMT2AMEN1 | |
| SCHEMBL6525810 | 0.80 | MAPT (0.57) | F10NAMPTGAAKMT2AMEN1 | |
| SCHEMBL10769628 | 0.80 | HDAC6 (0.58) | KDM4EHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8325725 | 0.79 | MAPT (0.55) | F10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL5428908 | 0.78 | F10 (0.60) | F10KMT2AMEN1ALDH1A1 | |
| SCHEMBL221944 | 0.76 | F10 (0.48) | F10KDM4EGAAKMT2AMEN1 | |
| SCHEMBL22353066 | 0.73 | MEN1 (0.52) | F10KDM4EGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4699985-B2 | — | — | 2011-06-15 | — | — | JP | claimed |