Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8808045 | 0.86 | TLR7 (0.44) | AGTR1AGTR2CTRCALDH1A1MAPT | |
| SCHEMBL1228189 | 0.77 | AGTR1 (0.53) | RARBAGTR1AGTR2CTRCALDH1A1 | |
| Acetic Acid SCHEMBL9254240 | 0.75 | AGTR1 (0.45) | RARBAGTR1AGTR2CTRCMEN1 | |
| SCHEMBL9254231 | 0.73 | AGTR1 (0.44) | RARBAGTR1AGTR2CTRC | |
| SCHEMBL181230 | 0.72 | RARB (0.89) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL1577579 | 0.72 | CTRC (0.53) | RARBAGTR1AGTR2CTRC | |
| SCHEMBL1321965 | 0.72 | KMT2A (0.39) | CTRCMEN1ALDH1A1KMT2A | |
| SCHEMBL29894181 | 0.71 | SRD5A2 (0.51) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9337767 | 0.70 | RARB (0.86) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL5448932 | 0.70 | RARB (0.86) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163521-A1 | Novel Pyrazolopyrimidinone Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-06-25 | — | — | US | disclosed |
| US-20090163521-A1 | Novel Pyrazolopyrimidinone Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-06-25 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| WO-2007000655-A2 | NOVEL PYRAZOLOPYRIMIDINONE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163521-A1 | Novel Pyrazolopyrimidinone Derivatives | CYP3A7, CYP3A5, CYP2C19 | RARB 4560/4885AGTR1 1221/4885AGTR2 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.