Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 2/20 | 0.45 |
| ▸ | GIPR | P48546 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096239 | 0.91 | HDAC1 (0.50) | HDAC1HDAC6PTGESGCGRNPC1 | |
| SCHEMBL2663021 | 0.83 | GCGR (0.58) | HDAC1HDAC6GCGRNPC1RAB9A | |
| SCHEMBL2663129 | 0.82 | GCGR (0.53) | HDAC1HDAC6GCGRMEN1KMT2A | |
| SCHEMBL2663018 | 0.80 | TRPV1 (0.61) | HDAC1HDAC6GCGRGLP1RGIPR | |
| SCHEMBL2654437 | 0.78 | S1PR1 (0.55) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2663053 | 0.77 | TRPV1 (0.62) | GCGRGLP1RGIPR | |
| SCHEMBL2654768 | 0.76 | S1PR1 (0.66) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4091181 | 0.76 | GCGR (0.67) | GCGRGLP1RGIPR | |
| SCHEMBL2662984 | 0.76 | GCGR (0.54) | HDAC1HDAC6GCGRSMN1; SMN2MEN1 | |
| SCHEMBL2663137 | 0.75 | ACHE (0.54) | HDAC1NPC1RAB9ASMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | GLP1R, GPR119, GCGR | HDAC1 2296/4885HDAC6 3537/4885PTGES 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.