Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952759 | 0.89 | LMNA (0.63) | LMNAPOLBKMT2AGAACYP1A2 | |
| SCHEMBL8219616 | 0.87 | KMT2A (0.65) | LMNAPOLBKMT2AGAACYP1A2 | |
| SCHEMBL1008891 | 0.78 | KDM4E (0.70) | LMNAGAACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12376759 | 0.76 | GAA (1.00) | LMNAPOLBKMT2AGAACYP1A2 | |
| SCHEMBL9566224 | 0.76 | NLN (0.60) | LMNAPOLBKMT2AGAACYP1A2 | |
| SCHEMBL13126955 | 0.76 | KMT2A (0.50) | LMNAPOLBKMT2AGAACYP1A2 | |
| SCHEMBL4582082 | 0.75 | TAAR1 (0.65) | LMNAGAACYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL8701162 | 0.75 | HDAC8 (0.58) | LMNAPOLBKMT2AGAACYP1A2 | |
| SCHEMBL8700358 | 0.75 | CYP1A2 (0.63) | LMNAKMT2AGAACYP1A2CYP2D6 | |
| SCHEMBL13801229 | 0.75 | TAAR1 (0.53) | LMNAPOLBKMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143363-A1 | Deuterated lorcaserin | CONCERT PHARMACEUTICALS, INC. (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143363-A1 | Deuterated lorcaserin | HTR2C, HTR3C, HTR4 | LMNA 1444/4885POLB 4862/4885KMT2A 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.