Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 19/20 | 0.68 |
| ▸ | DRD2 | P14416 | 17/20 | 0.68 |
| ▸ | DRD3 | P35462 | 14/20 | 0.68 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801366 | 0.86 | DRD4 (0.51) | DRD4DRD2DRD3 | |
| SCHEMBL14410182 | 0.84 | DRD4 (0.68) | DRD4DRD2DRD3MCHR1 | |
| SCHEMBL3962048 | 0.82 | DRD4 (0.65) | DRD4DRD2DRD3MCHR1 | |
| Hydrochloric Acid SCHEMBL8787588 | 0.81 | DRD4 (0.64) | DRD4DRD2DRD3MCHR1 | |
| SCHEMBL8786342 | 0.81 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8786357 | 0.79 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8785940 | 0.78 | DRD4 (0.80) | DRD4DRD2DRD3 | |
| SCHEMBL3957088 | 0.77 | DRD4 (0.58) | DRD4DRD2DRD3 | |
| SCHEMBL46402 | 0.75 | CHRM1 (0.67) | DRD2 | |
| SCHEMBL8786458 | 0.75 | DRD4 (1.00) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | DRD4 139/4885DRD2 187/4885DRD3 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.