Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 18/20 | 0.51 |
| ▸ | DRD2 | P14416 | 16/20 | 0.51 |
| ▸ | DRD3 | P35462 | 13/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801341 | 0.86 | DRD4 (0.68) | DRD4DRD2DRD3 | |
| SCHEMBL3963976 | 0.83 | DRD4 (0.47) | DRD4DRD2DRD3 | |
| SCHEMBL3960274 | 0.76 | GPR119 (0.49) | DRD4DRD2DRD3OPRM1 | |
| SCHEMBL13801266 | 0.75 | DRD4 (0.40) | DRD4DRD2DRD3OPRM1OPRK1 | |
| SCHEMBL46402 | 0.74 | CHRM1 (0.67) | DRD2OPRM1OPRK1OPRL1 | |
| SCHEMBL13801273 | 0.72 | DRD2 (0.67) | DRD4DRD2DRD3AKT1 | |
| SCHEMBL13801259 | 0.72 | SMN1; SMN2 (0.50) | OPRM1OPRK1OPRL1 | |
| SCHEMBL13801339 | 0.71 | CALCRL (0.46) | DRD4DRD2DRD3 | |
| SCHEMBL13801258 | 0.70 | TNKS (0.53) | DRD2OPRM1OPRK1OPRL1 | |
| SCHEMBL14410182 | 0.70 | DRD4 (0.68) | DRD4DRD2DRD3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | DRD4 139/4885DRD2 187/4885DRD3 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.