Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1267270 | 0.95 | HTR6 (0.64) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL43171 | 0.95 | HTR6 (0.64) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL451992 | 0.95 | HTR6 (0.64) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL943337 | 0.95 | HTR6 (0.64) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL28809524 | 0.93 | HTR6 (0.61) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL8695162 | 0.93 | HTR6 (0.61) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6499302 | 0.93 | HTR6 (0.61) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| Piperazine SCHEMBL27903046 | 0.93 | HTR6 (0.61) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL572044 | 0.93 | HTR6 (0.61) | HTR6OPRM1OPRL1OPRD1OPRK1 | |
| Water SCHEMBL14860181 | 0.93 | HTR6 (0.61) | HTR6OPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | HTR6 569/4885OPRM1 10/4885OPRL1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.