Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPX4 | P36969 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802095 | 0.93 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3913375 | 0.86 | RAB9A (0.40) | GPX4ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL3904664 | 0.84 | TP53 (0.40) | GPX4ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL13802104 | 0.83 | RAB9A (0.48) | ALDH1A1NPC1RAB9APAX8MEN1 | |
| SCHEMBL13802182 | 0.81 | KMT2A (0.41) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL13791235 | 0.81 | GPX4 (0.37) | GPX4ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL3901597 | 0.78 | RAB9A (0.37) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3905527 | 0.76 | MAPT (0.41) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL13791107 | 0.73 | CYP1A2 (0.37) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3913346 | 0.71 | RAB9A (0.51) | ALDH1A1NPC1RAB9APAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |