Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 2/20 | 0.61 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.61 |
| ▸ | ACLY | P53396 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802477 | 0.81 | AKR1C4 (0.78) | KCNK2KCNK10AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL418647 | 0.80 | SERPINE1 (0.66) | KCNK2KCNK10ACLYAKR1C2AKR1C1 | |
| SCHEMBL5225002 | 0.77 | HTT (0.70) | KCNK2KCNK10AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL8055373 | 0.74 | KMT2A (0.53) | KCNK2KCNK10AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL13802452 | 0.74 | AKR1C2 (0.78) | KCNK2KCNK10AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL21930987 | 0.73 | ACLY (1.00) | ACLYSERPINE1 | |
| SCHEMBL4825507 | 0.73 | P2RX1 (0.51) | KCNK2KCNK10P2RX1TMPRSS4MAPT | |
| SCHEMBL8058017 | 0.73 | MAPT (0.62) | AKR1C2AKR1C1AKR1C4AKR1C3RORC | |
| SCHEMBL4249335 | 0.73 | CTSV (0.71) | KCNK2KCNK10AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL4209269 | 0.73 | MAPT (0.70) | KCNK2KCNK10P2RX1TMPRSS4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | KCNK2 2183/4885KCNK10 2814/4885ACLY 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.