Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 3/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802443 | 0.78 | MAPT (0.74) | SERPINE1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL13802486 | 0.78 | MAPT (0.56) | RAB9AMAPTKMT2AMEN1GAA | |
| SCHEMBL13802458 | 0.74 | MAPT (0.48) | L3MBTL1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL13802482 | 0.74 | MAPT (0.52) | L3MBTL1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL3190849 | 0.74 | L3MBTL1 (0.65) | L3MBTL1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL28960367 | 0.74 | L3MBTL1 (0.57) | L3MBTL1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL5396641 | 0.71 | L3MBTL1 (0.69) | L3MBTL1MAPTKMT2AMEN1GAA | |
| SCHEMBL9178137 | 0.71 | L3MBTL1 (0.53) | L3MBTL1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL27711268 | 0.70 | MAPT (0.65) | L3MBTL1SERPINE1RAB9AMAPTKMT2A | |
| SCHEMBL2569392 | 0.70 | L3MBTL1 (0.67) | L3MBTL1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | L3MBTL1 4682/4885SERPINE1 1045/4885RAB9A 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.