SCHEMBL28960367

SCHEMBL28960367

CN(C)C(=O)c1ccc([N+](=O)[O-])cc1N[SH](=O)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.57
KMT2A Q03164 3/20 0.45
HPGD P15428 2/20 0.45
MEN1 O00255 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ALDH1A1 P00352 5/20 0.43
MAPT P10636 3/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MCL1 Q07820 1/20 0.41
HKDC1 Q2TB90 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KCNMA1 Q12791 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28511794 0.82 ALDH1A1 (0.55) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL28504947 0.82 SMN1; SMN2 (0.52) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL9178137 0.77 L3MBTL1 (0.53) L3MBTL1KMT2AHPGDMEN1NPSR1
SCHEMBL2569392 0.76 L3MBTL1 (0.67) L3MBTL1KMT2AHPGDMEN1NPSR1
SCHEMBL20401009 0.76 L3MBTL1 (0.77) L3MBTL1KMT2AHPGDMEN1NPSR1
SCHEMBL1781383 0.75 L3MBTL1 (0.65) L3MBTL1KMT2AHPGDMEN1NPSR1
SCHEMBL3190849 0.75 L3MBTL1 (0.65) L3MBTL1KMT2AHPGDMEN1NPSR1
SCHEMBL13802490 0.74 L3MBTL1 (0.49) L3MBTL1KMT2AHPGDMEN1ALDH1A1
SCHEMBL509411 0.73 L3MBTL1 (0.71) L3MBTL1KMT2AHPGDMEN1NPSR1
SCHEMBL31527794 0.73 ALDH1A1 (0.55) L3MBTL1KMT2AHPGDMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112125828-B Synthetic method of foramsulfuron intermediate 江苏省农用激素工程技术研究中心有限公司 2022-05-06 CN disclosed
CN-112125828-A Synthetic method of foramsulfuron intermediate 江苏省农用激素工程技术研究中心有限公司 2020-12-25 CN disclosed