Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190849 | 0.87 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL9334396 | 0.85 | RORC (0.52) | L3MBTL1KMT2AMEN1NPSR1RORC | |
| SCHEMBL9696161 | 0.83 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL509411 | 0.82 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL6071319 | 0.82 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL1762503 | 0.81 | KMT2A (0.61) | KMT2AMEN1NPSR1RORCSMN1; SMN2 | |
| SCHEMBL10953243 | 0.81 | HSD17B10 (0.62) | ALDH1A1KMT2AMEN1NPSR1RORC | |
| SCHEMBL5913520 | 0.81 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL18147340 | 0.81 | MAPT (0.52) | L3MBTL1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL20045614 | 0.81 | RORC (0.54) | L3MBTL1ALDH1A1KMT2AMEN1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189856-B2 | Central nervous system disorders; vision defects; antiproliferative agents | SHAPIRO GIDEON | 2007-03-13 | — | — | US | disclosed |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |
| US-20030191134-A1 | Non-peptide somatostatin receptor ligands | SHAPIRO GIDEON (US) | 2003-10-09 | — | — | US | disclosed |
| WO-2003057214-A1 | IMIDAZOLIDIN-2,4-DIONE DERIVATIVES AS NON-PEPTIDE SOMATOSTATIN RECEPTOR LIGANDS | SOMATOCOR PHARMACEUTICALS, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | SSTR1, SSTR3, NPY1R | L3MBTL1 2451/4885ALDH1A1 2632/4885KMT2A 2058/4885 |
| US-20030191134-A1 | Non-peptide somatostatin receptor ligands | SSTR2, SSTR1, SSTR3 | L3MBTL1 3005/4885ALDH1A1 4704/4885KMT2A 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.