Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 6/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7559739 | 0.99 | TNKS (0.38) | EEF2KTNKSPARP1TNKS2KCNH2 | |
| SCHEMBL6644175 | 0.82 | ALDH1A1 (0.44) | EEF2KTNKSJAK2JAK1JAK3 | |
| Hydrochloric Acid SCHEMBL7556675 | 0.81 | ALDH1A1 (0.43) | EEF2KTNKSJAK2JAK1JAK3 | |
| SCHEMBL4505813 | 0.79 | TOP2A (0.39) | EEF2KKCNH2CHRM1CHRM2CHRM4 | |
| SCHEMBL6646396 | 0.77 | EEF2K (0.37) | EEF2KKCNH2CHRM1CHRM2CHRM4 | |
| SCHEMBL6668566 | 0.77 | EEF2K (0.37) | EEF2KKCNH2CHRM1CHRM2CHRM4 | |
| SCHEMBL1383138 | 0.77 | PARP1 (0.40) | EEF2KPARP1CHRM1CHRM2CHRM4 | |
| SCHEMBL6670008 | 0.75 | JAK2 (0.39) | EEF2KKCNH2CHRM1CHRM2CHRM4 | |
| SCHEMBL1381428 | 0.74 | OPRM1 (0.45) | EEF2KTNKSPARP1CHRM1HSD11B1 | |
| SCHEMBL12835810 | 0.73 | EEF2K (0.41) | EEF2KJAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4811978-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | claimed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | claimed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | claimed |