Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | LITAF | Q99732 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16787434 | 0.81 | DAO (0.57) | DAOJAK2JAK1JAK3HSD11B1 | |
| SCHEMBL1380290 | 0.77 | EEF2K (0.39) | PARP1JAK2JAK1JAK3HSD11B1 | |
| Hydrochloric Acid SCHEMBL7559739 | 0.75 | TNKS (0.38) | PARP1JAK2JAK1JAK3MEN1 | |
| SCHEMBL1380522 | 0.74 | PARP1 (0.44) | PARP1DAO | |
| SCHEMBL31285881 | 0.74 | DAO (0.51) | DAOJAK2JAK3HSD11B1CHRM2 | |
| SCHEMBL7555382 | 0.74 | JAK2 (0.40) | JAK2JAK1JAK3ALDH1A1TYK2 | |
| SCHEMBL3632106 | 0.74 | DAO (0.51) | DAOJAK2JAK3HSD11B1CHRM2 | |
| Bromide SCHEMBL6247940 | 0.72 | DAO (0.50) | DAOJAK2JAK3HSD11B1CHRM2 | |
| SCHEMBL29643238 | 0.71 | ALKBH5 (0.56) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16819110 | 0.70 | JAK2 (0.41) | DAOJAK2JAK1JAK3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4811978-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |